Description

1-(Toluene-4-Sulfonyl)-Imidazo[1,5-A]Pyridine is a high-purity, specialized heterocyclic sulfonamide building block of significant interest in advanced organic synthesis. Its core value lies in its role as a key intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process R&D teams in the pharmaceutical, agrochemical, and material science industries who require reliable, high-quality intermediates for lead optimization and scale-up activities.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the discovery and synthesis of new crop protection agents and pesticides, leveraging its fused heterocyclic structure.
• Material Science Precursor: Serves as a precursor for organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for organic light-emitting diodes (OLEDs).
• Chemical Biology Probe Development: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring this specific sulfonylated imidazopyridine scaffold.

Basic Information

Product Name	1-(Toluene-4-Sulfonyl)-Imidazo[1,5-A]Pyridine
CAS No.	904813-28-1
Molecular Formula	C14H12N2O2S
Molecular Weight	272.32 g/mol
Synonyms	1-(p-Toluenesulfonyl)imidazo[1,5-a]pyridine; 1-Tosylimidazo[1,5-a]pyridine; Imidazo[1,5-a]pyridine, 1-[(4-methylphenyl)sulfonyl]-; 1-(4-Methylbenzenesulfonyl)imidazo[1,5-a]pyridine; 904813-28-1; 1-(Toluene-4-sulfonyl)imidazo[1,5-a]pyridine
EINECS	Contact for details

Quality Control

Our 1-(Toluene-4-Sulfonyl)-Imidazo[1,5-A]Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring a reliable supply for research and development purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.