Description

1-Cyclobutylethanamine Hydrochloride is a high-purity organic salt of significant interest in advanced chemical synthesis. This compound serves as a crucial chiral building block and intermediate for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors seeking to develop new molecular entities with enhanced properties.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents, particularly in central nervous system (CNS) and metabolic disorder drug candidates.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the cyclobutyl moiety can contribute to unique biological activity.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Production: Employed in the multistep synthesis of complex, high-value specialty chemicals and flavors & fragrances.
• Academic and R&D Laboratories: Used as a reference standard and building block in medicinal chemistry and organic synthesis research programs.
• Peptidomimetic Chemistry: The amine functionality makes it a valuable component for constructing novel peptide analogs and bioisosteres.

Basic Information

Product Name	1-Cyclobutylethanamine Hydrochloride
CAS No.	904733-73-9
Molecular Formula	C6H14ClN
Molecular Weight	135.63 g/mol
Synonyms	1-Cyclobutylethan-1-amine hydrochloride; (1-Cyclobutylethyl)amine hydrochloride; α-Methylcyclobutanemethylamine hydrochloride; 1-(1-Aminoethyl)cyclobutane hydrochloride; Cyclobutylmethylamine, α-methyl-, hydrochloride; 1-Cyclobutyl-1-ethanamine HCl
EINECS	Contact for details

Quality Control

Our 1-Cyclobutylethanamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and residual solvent screening, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and conformance to agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). Keep the container tightly sealed under an inert atmosphere to minimize exposure to moisture and ensure long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee (if applicable)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.