Description

8-Bromo-5-Fluoro-2-Methyl-Quinoline is a high-purity, halogenated quinoline derivative serving as a critical building block in advanced organic synthesis. Its value lies in its unique molecular scaffold, which is essential for constructing complex molecules with tailored biological and material properties. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other therapeutic agents.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, leveraging the bioactivity of the quinoline core.
• Material Science: Serves as a monomer or functional unit in the creation of organic semiconductors, luminescent materials, and metal-organic frameworks (MOFs).
• Chemical Biology: Employed as a molecular probe or tag due to its fluorinated and brominated handles for further functionalization via cross-coupling reactions.
• Academic & Contract Research: Essential for methodological development in organic synthesis, including Suzuki, Stille, and other palladium-catalyzed coupling reactions.

Basic Information

Product Name	8-Bromo-5-Fluoro-2-Methyl-Quinoline
CAS No.	904694-59-3
Molecular Formula	C₁₀H₇BrFN
Molecular Weight	240.07 g/mol
Synonyms	8-Bromo-5-fluoro-2-methylquinoline; 2-Methyl-8-bromo-5-fluoroquinoline; Quinoline, 8-bromo-5-fluoro-2-methyl-; 904694-59-3; 5-Fluoro-8-bromo-2-methylquinoline; 8-Br-5-F-2-Me-Quinoline
EINECS	Contact for details

Quality Control

Our 8-Bromo-5-Fluoro-2-Methyl-Quinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.