Description

1-Ethynyl-4-Fluoronaphthalene is a high-value, multi-functional fluorinated naphthalene derivative featuring a reactive ethynyl group. This compound serves as a critical advanced intermediate for constructing complex molecular architectures in pharmaceutical and materials science research. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and organic electronics sectors for synthesizing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, especially in oncology and CNS therapeutic areas.
• Agrochemical Research: Used in developing novel pesticides and herbicides by incorporating the fluoronaphthalene scaffold.
• Material Science: Serves as a monomer or cross-linker in the production of specialized polymers and organic semiconductors for OLEDs.
• Chemical Synthesis: Utilized in Sonogashira coupling and other metal-catalyzed reactions to create conjugated systems and complex aromatic structures.
• Ligand & Catalyst Development: Acts as a precursor for creating specialized ligands used in homogeneous catalysis.
• Fluorescent Probe Synthesis: The fluoronaphthalene core is valuable for developing fluorescent tags and sensors for biochemical applications.

Basic Information

Item	Details
Product Name	1-Ethynyl-4-Fluoronaphthalene
CAS No.	904694-35-5
Molecular Formula	C₁₂H₇F
Molecular Weight	170.18 g/mol
Synonyms	4-Fluoro-1-ethynylnaphthalene; 1-Ethynyl-4-fluoronaphthalene; 1-(Fluoronaphthalen-4-yl)ethyne; 4-Ethynyl-1-fluoronaphthalene; Naphthalene, 1-ethynyl-4-fluoro-
EINECS	Contact for details

Quality Control

Every batch of 1-Ethynyl-4-Fluoronaphthalene is manufactured and analyzed under strict quality management protocols to ensure high purity and batch-to-batch consistency. Our standard offering typically meets a purity specification of ≥97% (by HPLC), with custom purification available. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C or as specified on the CoA. This compound is easily oxidized and should be handled in a moisture-free environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.