Description

6-Bromo-4-Chloroquinoline-2-Carboxaldehyde is a versatile and high-value halogenated quinoline derivative, serving as a critical building block in advanced organic synthesis. Its unique bifunctional structure, featuring both bromo and chloro substituents alongside a reactive aldehyde group, makes it indispensable for constructing complex heterocyclic frameworks. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel quinoline-based drug candidates, particularly for applications in oncology, anti-infectives, and central nervous system (CNS) disorders.
• Agrochemical Research: Used to develop new herbicides, fungicides, and insecticides, leveraging the bioactivity of the quinoline core.
• Material Science: Serves as a monomer or functionalizing agent in the creation of organic electronic materials, ligands for catalysts, and specialty polymers.
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and as a scaffold for constructing libraries of diverse heterocyclic compounds in medicinal chemistry.
• Academic & Contract Research: Essential for fundamental research in organic methodology development and structure-activity relationship (SAR) studies.

Basic Information

Product Name	6-Bromo-4-Chloroquinoline-2-Carboxaldehyde
CAS No.	904369-49-9
Molecular Formula	C10H5BrClNO
Molecular Weight	270.51 g/mol
Synonyms	4-Chloro-6-bromoquinoline-2-carboxaldehyde; 2-Formyl-6-bromo-4-chloroquinoline; 6-Bromo-4-chloro-2-quinolinecarboxaldehyde; 6-Bromo-4-chloroquinoline-2-carbaldehyde; Quinoline-2-carboxaldehyde, 6-bromo-4-chloro-; 904369-49-9 (CAS)
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for all our advanced intermediates. Each batch of 6-Bromo-4-Chloroquinoline-2-Carboxaldehyde is analyzed using advanced techniques including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. Our quality system is designed to support cGMP and ISO standards for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity, the product should be stored under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC / NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.