Description

n-Hydroxy-4-Nitro-3-(Trifluoromethyl)Aniline (Flu-1-n-Oh) is a specialized aromatic amine derivative featuring both nitro and trifluoromethyl substituents, which confer unique electronic and steric properties. This compound serves as a high-value pharmaceutical intermediate and a versatile building block in advanced organic synthesis. It is primarily required by R&D laboratories and production facilities in the pharmaceutical, agrochemical, and specialty chemical sectors for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting specific enzyme pathways.
• Agrochemical Synthesis: Used in the research and development of new herbicides and pesticides, leveraging the biological activity of the nitroaniline core.
• Material Science: Acts as a monomer or functionalizing agent for creating advanced polymers with specific optical or electronic properties.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, nucleophilic substitutions, and as a directing group in metal-catalyzed transformations due to its hydroxyl and nitro functionalities.
• Dye and Pigment Intermediate: Serves in the development of specialized colorants and photographic chemicals.
• Research & Development: Essential for academic and industrial research in medicinal chemistry and chemical biology for structure-activity relationship (SAR) studies.

Basic Information

Product Name	n-Hydroxy-4-Nitro-3-(Trifluoromethyl)Aniline (Flu-1-n-Oh)
CAS No.	904328-95-6
Molecular Formula	C7H5F3N2O3
Molecular Weight	222.12 g/mol
Synonyms	4-Nitro-3-(trifluoromethyl)aniline N-oxide; 3-(Trifluoromethyl)-4-nitroaniline N-oxide; 4-Nitro-3-(trifluoromethyl)phenylhydroxylamine; Flu-1-n-Oh; 904328-95-6; N-Hydroxy-4-nitro-3-trifluoromethylaniline; 3-Trifluoromethyl-4-nitro-N-hydroxyaniline
EINECS	Contact for details

Quality Control

Our n-Hydroxy-4-Nitro-3-(Trifluoromethyl)Aniline is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications in regulated environments, including cGMP for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.