Description

Methyl 3-Amino-2,3-Dihydro-1H-Indene-5-Carboxylate Hydrochloride is a high-purity, pharmaceutically relevant intermediate characterized by its fused indane ring structure. This compound is of significant value for its role as a key building block in the synthesis of complex bioactive molecules, particularly in medicinal chemistry. It is primarily sought after by research institutions and pharmaceutical development companies engaged in the creation of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of drug candidates targeting central nervous system (CNS) disorders, cardiovascular diseases, and other therapeutic areas.
• Medicinal Chemistry Research: Used extensively in lead optimization and structure-activity relationship (SAR) studies due to its versatile chemical scaffold.
• API Development: Employed in the development and scale-up processes for Active Pharmaceutical Ingredients (APIs) requiring the indane core structure.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for client projects.

Basic Information

Product Name	Methyl 3-Amino-2,3-Dihydro-1H-Indene-5-Carboxylate Hydrochloride
CAS No.	903558-73-6
Molecular Formula	C11H14ClNO2
Molecular Weight	227.69 g/mol
Synonyms	5-Carbomethoxy-3-aminoindane hydrochloride; Methyl 3-aminoindane-5-carboxylate hydrochloride; 3-Amino-2,3-dihydro-1H-indene-5-carboxylic acid methyl ester hydrochloride; 1H-Indene-5-carboxylic acid, 3-amino-2,3-dihydro-, methyl ester, hydrochloride; 903558-73-6; Methyl 3-amino-2,3-dihydro-1H-indene-5-carboxylate HCl
EINECS	Contact for details

Quality Control

Our Methyl 3-Amino-2,3-Dihydro-1H-Indene-5-Carboxylate Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and production. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.