Description

8-Bromo-2-Chloroquinoline-4-Carboxylic Acid is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound is particularly significant for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and specialty agrochemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel quinoline-based drug candidates, including potential antimicrobials, anticancer agents, and kinase inhibitors.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides, fungicides, and pesticides with enhanced efficacy.
• Material Science Research: Serves as a building block for creating functional organic materials, such as ligands for metal-organic frameworks (MOFs) or organic semiconductors.
• Chemical Biology: Employed in the design and synthesis of molecular probes and inhibitors for studying biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up production under cGMP or ISO standards.

Basic Information

Product Name	8-Bromo-2-Chloroquinoline-4-Carboxylic Acid
CAS No.	902743-27-5
Molecular Formula	C10H5BrClNO2
Molecular Weight	286.51 g/mol
Synonyms	8-Bromo-2-chloro-4-quinolinecarboxylic acid; 2-Chloro-8-bromoquinoline-4-carboxylic acid; 4-Quinolinecarboxylic acid, 8-bromo-2-chloro-; 902743-27-5; 8-Bromo-2-chloroquinoline-4-carboxylate; 8-Br-2-Cl-quinoline-4-COOH
EINECS	Contact for details

Quality Control

Our 8-Bromo-2-Chloroquinoline-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates for research and cGMP manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.