Description

6,8-Difluoro-4-Chloroquinoline-2-Carboxylic Acid is a high-purity, multi-functional heterocyclic building block of significant importance in advanced organic synthesis. This compound is valued for its unique molecular scaffold, which serves as a critical precursor in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for creating complex molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel quinoline-based drug candidates, particularly in antimicrobial and anticancer research.
• Agrochemical Development: Used in the research and production of advanced herbicides and fungicides, leveraging the bioactivity of the difluoro-chloroquinoline core.
• Organic Synthesis Building Block: Serves as a versatile precursor for constructing complex heterocyclic systems in medicinal and process chemistry.
• Material Science Research: Investigated as a monomer or additive for creating specialty polymers and functional materials with specific electronic or photophysical properties.
• Chemical Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	6,8-Difluoro-4-Chloroquinoline-2-Carboxylic Acid
CAS No.	902742-65-8
Molecular Formula	C10H4ClF2NO2
Molecular Weight	243.60 g/mol
Synonyms	4-Chloro-6,8-difluoroquinoline-2-carboxylic acid; 2-Quinolinecarboxylic acid, 4-chloro-6,8-difluoro-; 6,8-Difluoro-4-chloro-2-quinolinecarboxylic acid; 902742-65-8; Difluoro-chloroquinoline carboxylic acid; 4-Chloro-6,8-difluoro-2-quinolinecarboxylic acid
EINECS	Contact for details

Quality Control

Our 6,8-Difluoro-4-Chloroquinoline-2-Carboxylic Acid is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality system supports development from research to commercial scale, ensuring reliable supply for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The product is light-sensitive (store away from light) and should be handled with appropriate precautions for strong acids/organic solvents. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.