Description

8-Bromo-4-Chloroquinoline-2-Carboxylic Acid is a high-purity, multi-functional heterocyclic building block of significant importance in advanced organic synthesis. Its core value lies in its versatile reactivity, serving as a key precursor for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality intermediates for their synthetic workflows.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel quinoline-based drug candidates, including potential antimicrobials, anticancer agents, and kinase inhibitors.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, leveraging the bioactivity of the quinoline scaffold.
• Material Science: Serves as a precursor for creating organic ligands in coordination chemistry and for synthesizing advanced organic electronic materials.
• Chemical Synthesis: Utilized in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and functional group transformations to introduce complexity into target molecules.
• Academic & R&D: A valuable reagent for methodological studies and exploring new reaction pathways in heterocyclic and medicinal chemistry.

Basic Information

Product Name	8-Bromo-4-Chloroquinoline-2-Carboxylic Acid
CAS No.	902742-60-3
Molecular Formula	C10H5BrClNO2
Molecular Weight	286.51 g/mol
Synonyms	8-Bromo-4-chloro-2-quinolinecarboxylic acid; 2-Quinolinecarboxylic acid, 8-bromo-4-chloro-; 4-Chloro-8-bromoquinoline-2-carboxylic acid; 8-Bromo-4-chloroquinaldinic acid; 902742-60-3; 8-Br-4-Cl-quinoline-2-COOH
EINECS	Contact for details

Quality Control

Our 8-Bromo-4-Chloroquinoline-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our commitment to supply chain reliability and batch-to-batch consistency supports your R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light sources to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.