Description

9-Chloro-5,6,7,8-Tetrahydroacridine-3-Carboxylic Acid is a high-purity, synthetically derived heterocyclic carboxylic acid building block of significant interest in advanced pharmaceutical research and development. Its core value lies in its versatile molecular scaffold, which serves as a critical precursor for synthesizing novel compounds with targeted biological activity. This intermediate is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel acridine-based drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Chemical Biology Probe Development: Used to create molecular probes for studying enzyme mechanisms and protein-ligand interactions due to its modifiable core structure.
• Agrochemical Research: Serves as a precursor in the development of new herbicides and pesticides with specific modes of action.
• Material Science Applications: Utilized in the synthesis of organic semiconductors, ligands for metal-organic frameworks (MOFs), and other functional organic materials.
• Academic & Contract Research: Essential for universities and CROs (Contract Research Organizations) conducting fundamental research in medicinal and synthetic chemistry.
• Process Chemistry & Scale-Up: Employed in route scouting and optimization for the commercial-scale production of complex molecules.

Basic Information

Product Name	9-Chloro-5,6,7,8-Tetrahydroacridine-3-Carboxylic Acid
CAS No.	902586-59-8
Molecular Formula	C₁₄H₁₂ClNO₂
Molecular Weight	261.70 g/mol
Synonyms	9-Chloro-5,6,7,8-tetrahydroacridine-3-carboxylic acid; 9-Chloro-3-carboxy-5,6,7,8-tetrahydroacridine; 3-Carboxy-9-chloro-5,6,7,8-tetrahydroacridine; THA-9-Cl-3-COOH; Acridine-3-carboxylic acid, 9-chloro-5,6,7,8-tetrahydro-; 902586-59-8; 9-Cl-THAC-3-COOH
EINECS	Contact for details

Quality Control

Our 9-Chloro-5,6,7,8-Tetrahydroacridine-3-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and MS, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.