Description

1-(3-Iodo-Benzyl)-Piperidine-4-Carboxylic Acid is a high-purity, versatile piperidine-based building block and intermediate of significant interest in advanced organic synthesis. Its molecular architecture, featuring both a carboxylic acid and a halogenated benzyl group, makes it a critical precursor for constructing complex pharmacophores and functional materials. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active compounds or novel chemical entities.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, receptor modulators, and enzyme inhibitors.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, or plant growth regulators, leveraging its halogenated aromatic system for bioactivity.
• Ligand and Catalyst Synthesis: Serves as a precursor for creating complex ligands used in asymmetric catalysis or metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and protein functions.
• Peptidomimetics & Scaffold Development: The piperidine-carboxylic acid core is valuable for constructing conformationally constrained peptide mimics and diverse heterocyclic scaffolds.
• Material Science Precursor: Potential use in synthesizing specialty polymers or organic electronic materials with tailored properties.

Basic Information

Product Name	1-(3-Iodo-Benzyl)-Piperidine-4-Carboxylic Acid
CAS No.	901922-29-0
Molecular Formula	C13H16INO2
Molecular Weight	345.18 g/mol
Synonyms	1-[(3-Iodophenyl)methyl]piperidine-4-carboxylic acid; 4-Piperidinecarboxylic acid, 1-[(3-iodophenyl)methyl]-; 1-(3-Iodobenzyl)isonipecotic acid; 901922-29-0; 1-(3-Iodobenzyl)-4-piperidinecarboxylic acid; 1-(3-Iodobenzyl)piperidine-4-carboxylic acid; 1-(3-Iodobenzyl)piperidine-4-carboxylate
EINECS	Contact for details

Quality Control

Our 1-(3-Iodo-Benzyl)-Piperidine-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.