Description

1-(3-Bromobenzyl)Piperidine-4-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate and versatile building block in organic synthesis. This compound matters for its crucial role in the research and development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and receptor-targeted therapies. Pharmaceutical R&D laboratories, agrochemical innovators, and specialty chemical manufacturers need this material for constructing complex molecular architectures with precision.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting neurological and psychiatric disorders.
• Organic Synthesis Building Block: Used in amide coupling, esterification, and other reactions to introduce the piperidine-4-carboxylic acid moiety with a bromobenzyl handle for further functionalization.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and library synthesis for high-throughput screening in drug discovery programs.
• Ligand and Receptor Probe Development: Serves as a core structure for developing selective ligands for sigma receptors or other G-protein-coupled receptors (GPCRs).
• Agrochemical Intermediate: Potential use in the synthesis of advanced crop protection agents and pesticides.
• Chemical Biology Tool Compound: Used to create probes for studying enzyme function and biological pathways.

Basic Information

Product Name	1-(3-Bromobenzyl)Piperidine-4-Carboxylic Acid
CAS No.	901920-76-1
Molecular Formula	C13H16BrNO2
Molecular Weight	298.18 g/mol
Synonyms	4-Piperidinecarboxylic acid, 1-[(3-bromophenyl)methyl]-; 1-[(3-Bromophenyl)methyl]piperidine-4-carboxylic acid; 1-(3-Bromobenzyl)-4-piperidinecarboxylic acid; 1-(3-Bromobenzyl)isonipecotic acid; 3-Bromobenzyl isonipecotate (precursor related); Isonipecotic acid, 1-(3-bromobenzyl)-; 901920-76-1 (CAS Registry)
EINECS	Contact for details

Quality Control

Our 1-(3-Bromobenzyl)Piperidine-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.