Description

n-[(1-Isopropyl-2-Pyrrolidinyl)Methyl]-1-Propanamine is a specialized pyrrolidine derivative with a branched alkylamine structure, serving as a valuable chiral intermediate in advanced organic synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and fine chemicals where stereochemical control is critical. It is needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications ranging from medicinal chemistry to catalyst ligand synthesis.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of novel therapeutic agents, particularly for central nervous system (CNS) targets.
• Catalyst Ligand Precursor: Used in the preparation of chiral ligands for asymmetric catalysis, enabling enantioselective transformations.
• Agrochemical Synthesis: Serves as an intermediate in the development of advanced, stereochemically-defined pesticides and herbicides.
• Fine Chemical Production: Employed in the multistep synthesis of complex, high-value specialty chemicals and flavors/fragrances.
• Academic & Industrial Research: A valuable reagent for methodological development in organic chemistry and drug discovery programs.
• Chemical Reference Standard: Used as an analytical standard for quality control and regulatory submissions in pharmaceutical manufacturing.

Basic Information

Product Name	n-[(1-Isopropyl-2-Pyrrolidinyl)Methyl]-1-Propanamine
CAS No.	901585-75-9
Molecular Formula	C12H26N2
Molecular Weight	198.35 g/mol
Synonyms	1-Propanamine, N-[(1-isopropyl-2-pyrrolidinyl)methyl]-; 1-[(1-Isopropylpyrrolidin-2-yl)methyl]propylamine; N-[(1-Isopropyl-2-pyrrolidinyl)methyl]propylamine; (S)- or (R)- enantiomers may be specified; 1-Isopropyl-2-(propylaminomethyl)pyrrolidine; Pyrrolidine, 2-[(propylamino)methyl]-1-(1-methylethyl)-; A potential intermediate for Iloperidone synthesis.
EINECS	Contact for details

Quality Control

Our n-[(1-Isopropyl-2-Pyrrolidinyl)Methyl]-1-Propanamine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and can be tailored to meet specific customer or regulatory requirements (e.g., ICH guidelines).

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (enantiomer specified)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.