Description

2-(3-Methoxy-Phenyl)-Cyclopropanecarboxylic Acid is a high-purity, synthetically versatile cyclopropane derivative, serving as a critical chiral building block in advanced organic synthesis. Its unique structural motif, combining a cyclopropane ring with a methoxy-substituted aromatic system, makes it an indispensable intermediate for constructing complex molecular architectures with precise stereochemistry. This compound is primarily utilized by research institutions and pharmaceutical development companies engaged in the creation of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel therapeutic agents, particularly in central nervous system (CNS) and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the cyclopropane moiety can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis to achieve high enantioselectivity.
• Material Science Research: Employed in the synthesis of specialty polymers and liquid crystals, where its rigid structure can influence material properties.
• Chemical Biology Probes: Utilized as a scaffold for developing molecular probes to study enzyme mechanisms and biological pathways.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes under cGMP conditions.

Basic Information

Product Name	2-(3-Methoxy-Phenyl)-Cyclopropanecarboxylic Acid
CAS No.	900254-25-3
Molecular Formula	C11H12O3
Molecular Weight	192.21 g/mol
Synonyms	2-(3-Methoxyphenyl)cyclopropanecarboxylic acid; 1-(3-Methoxyphenyl)cyclopropane-1-carboxylic acid; 3-Methoxyphenylcyclopropanecarboxylic Acid; (3-Methoxyphenyl)cyclopropanecarboxylic Acid; Cyclopropanecarboxylic acid, 2-(3-methoxyphenyl)-; 900254-25-3; 2-(3-Methoxy-phenyl)-cyclopropanecarboxylic acid
EINECS	Contact for details

Quality Control

Our 2-(3-Methoxy-Phenyl)-Cyclopropanecarboxylic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We employ advanced analytical techniques including HPLC, GC, NMR, and IR spectroscopy for verification. Our quality commitment aligns with ICH guidelines, and we support development from research to commercial scale with appropriate documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%
Optical Purity (Chiral HPLC)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.