Description

Dichloro[1,3-Bis(2,4,6-Trimethylphenyl)-2-Imidazolidinylidene](Benzylidene)Bis(3-Bromopyridine)Ruthenium(II) is a highly specialized, second-generation Grubbs-Hoveyda type olefin metathesis catalyst. This compound matters for its exceptional thermal stability and functional group tolerance, enabling complex synthetic transformations under mild conditions. It is a critical reagent for researchers and process chemists in pharmaceutical development, advanced materials science, and specialty chemical synthesis, where precision and catalyst longevity are paramount.

Application

• Pharmaceutical Intermediate Synthesis: Enabling key ring-closing metathesis (RCM), cross-metathesis (CM), and ring-opening metathesis polymerization (ROMP) steps in the production of active pharmaceutical ingredients (APIs).
• Advanced Polymer & Material Science: Facilitating the controlled synthesis of specialty polymers, functionalized materials, and self-healing composites via ROMP.
• Agrochemical Research: Used in the development of novel, complex molecular architectures for new crop protection agents.
• Fine Chemical & Fragrance Manufacturing: Critical for constructing challenging carbon-carbon double bonds in high-value, low-volume specialty chemicals.
• Academic & Industrial R&D: A staple catalyst for methodology development and exploring new reaction pathways in organic synthesis laboratories worldwide.
• Process Chemistry Optimization: Valued for its robustness in scaling up metathesis reactions from milligram to kilogram scale in pilot plants.

Basic Information

Product Name	Dichloro[1,3-Bis(2,4,6-Trimethylphenyl)-2-Imidazolidinylidene](Benzylidene)Bis(3-Bromopyridine)Ruthenium(II)
CAS No.	900169-53-1
Molecular Formula	C39H40Br2Cl2N4Ru
Molecular Weight	882.57 g/mol
Synonyms	Grubbs-Hoveyda Catalyst 2nd Generation, 3-Bromopyridine Derivative; Hoveyda-Grubbs Catalyst 2nd Gen, Brominated; [1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene]dichloro(o-isopropoxyphenylmethylene)ruthenium(II) analogue; Dichloro(o-isopropoxyphenylmethylene)(1,3-bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)ruthenium(II) with 3-Bromopyridine ligands; Ru-based Olefin Metathesis Catalyst; (H2IMes)(3-Br-py)2(Cl)2Ru=CHPh Complex
EINECS	Contact for details

Quality Control

Our Dichloro[1,3-Bis(2,4,6-Trimethylphenyl)-2-Imidazolidinylidene](Benzylidene)Bis(3-Bromopyridine)Ruthenium(II) is manufactured and handled under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR (1H, 13C), HPLC for purity assessment, and elemental analysis to ensure identity, potency, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C or as specified on the label. This material is moisture-sensitive and easily oxidized; ensure containers are sealed immediately after use to exclude air and moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Dark green to brown crystalline solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Solubility	Soluble in common organic solvents (DCM, toluene, THF)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.