Description

2-Amino-4-Iodo-Phenol is a halogenated aniline derivative of significant interest in advanced organic synthesis. This compound serves as a versatile and critical building block for the development of complex molecules, particularly in pharmaceutical and agrochemical research. Its unique structure, featuring both an amino and a hydroxyl group ortho to an iodine atom, makes it a valuable precursor for coupling reactions and the synthesis of heterocyclic compounds. Industries engaged in fine chemical manufacturing, material science, and life science R&D will find this high-purity intermediate essential for their innovative processes.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those with iodinated aromatic structures for diagnostic or therapeutic agents.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators.
• Dye and Pigment Manufacturing: Serves as a building block for specialized azo dyes and colorants requiring halogenated phenols for enhanced properties.
• Material Science Research: Employed in the creation of organic electronic materials, ligands for catalysts, and advanced polymers.
• Chemical Research & Development: A versatile reagent for Suzuki, Buchwald-Hartwig, and other palladium-catalyzed cross-coupling reactions.
• Life Science Reagents: Used in the preparation of biochemical probes, imaging agents, and other research tools.

Basic Information

Item	Details
Product Name	2-Amino-4-Iodo-Phenol
CAS No.	99969-17-2
Molecular Formula	C6H6INO
Molecular Weight	235.03 g/mol
Synonyms	4-Iodo-2-aminophenol; 2-Amino-4-iodophenol; 4-Iodo-2-hydroxyaniline; 2-Hydroxy-4-iodoaniline; 1-Amino-2-hydroxy-5-iodobenzene; Phenol, 2-amino-4-iodo-; 5-Iodo-2-aminophenol
EINECS	Contact for details

Quality Control

Our 2-Amino-4-Iodo-Phenol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity determination, residual solvent analysis, and identification by FT-IR and NMR spectroscopy. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring suitability for demanding R&D and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Light yellow to brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.