Description

3-Acetyl-6-Bromoquinolin-4(1H)-One is a high-purity brominated quinoline derivative, a crucial advanced intermediate in modern organic synthesis. Its value lies in its functionalized heterocyclic structure, which serves as a versatile building block for constructing complex molecules with targeted biological activity. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting kinase inhibition or other therapeutic pathways where the quinoline scaffold is relevant.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides, leveraging its halogenated structure for bioactivity.
• Material Science: Serves as a building block for creating organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components in organic light-emitting diodes (OLEDs).
• Chemical Synthesis: Acts as a versatile synthon for further functionalization via cross-coupling reactions (e.g., Suzuki, Sonogashira) or nucleophilic substitution, facilitated by the bromine atom.
• Dye and Pigment Intermediate: Utilized in the research and production of specialized quinoline-based dyes and colorants.

Basic Information

Product Name	3-Acetyl-6-Bromoquinolin-4(1H)-One
CAS No.	99867-16-0
Molecular Formula	C₁₁H₈BrNO₂
Molecular Weight	266.09 g/mol
Synonyms	6-Bromo-3-acetyl-4-hydroxyquinoline; 3-Acetyl-6-bromo-4-quinolone; 6-Bromo-3-acetyl-4(1H)-quinolinone; 4-Hydroxy-6-bromo-3-quinolinecarboxaldehyde; 99867-16-0; 3-Acetyl-6-bromoquinolin-4-ol; 6-Bromo-3-acetyl-1,4-dihydroquinolin-4-one
EINECS	Contact for details

Quality Control

Our 3-Acetyl-6-Bromoquinolin-4(1H)-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and support our products with a detailed Certificate of Analysis (COA) available upon request, confirming compliance with customer specifications and relevant industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.