Description

4-Chloro-2-Methylquinoline-6-Carbonitrile is a high-purity, versatile quinoline derivative that serves as a critical building block in advanced organic synthesis. Its unique halogenated and nitrile-substituted structure makes it an invaluable intermediate for developing complex molecules with targeted biological and material properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for applications in drug discovery, crop protection, and functional material development.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for compounds with quinoline-based scaffolds.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Organic Light-Emitting Diodes (OLEDs): Acts as a starting material for synthesizing electron-transport or emissive layer materials in electronic displays.
• Ligand Synthesis: Building block for creating complex chelating ligands used in catalysis and metal-organic frameworks (MOFs).
• Dye and Pigment Manufacturing: Intermediate for producing specialized quinoline-based dyes with specific colorfastness and stability properties.
• Academic & Contract Research: Essential reagent for methodological studies in organic chemistry and medicinal chemistry research programs.

Basic Information

Product Name	4-Chloro-2-Methylquinoline-6-Carbonitrile
CAS No.	99866-48-5
Molecular Formula	C11H7ClN2
Molecular Weight	202.64 g/mol
Synonyms	6-Cyano-4-chloro-2-methylquinoline; 4-Chloro-2-methyl-6-quinolinecarbonitrile; 2-Methyl-4-chloroquinoline-6-carbonitrile; Quinoline, 4-chloro-2-methyl-6-cyano-; 99866-48-5; 4-Chloro-2-methylquinoline-6-carbonitrile
EINECS	Contact for details

Quality Control

Every batch of 4-Chloro-2-Methylquinoline-6-Carbonitrile is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and industrial synthesis. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat sources and incompatible materials. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.