Description

8-Methyl-3-Methylene-8-Aza-Bicyclo[3.2.1]Octane is a specialized bicyclic amine derivative with a unique bridged-ring structure, serving as a critical advanced intermediate in organic synthesis. Its rigid molecular framework makes it a valuable building block for constructing complex pharmacologically active molecules and fine chemicals. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients or functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for compounds targeting the central nervous system.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides that require complex amine scaffolds.
• Ligand and Catalyst Development: Serves as a backbone for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, dyes, and performance materials where its bicyclic structure imparts specific properties.
• Academic and Industrial R&D: A valuable tool for methodological studies in organic chemistry and for exploring new chemical spaces in drug discovery programs.

Basic Information

Product Name	8-Methyl-3-Methylene-8-Aza-Bicyclo[3.2.1]Octane
CAS No.	99838-33-2
Molecular Formula	C9H15N
Molecular Weight	137.22 g/mol
Synonyms	8-Methyl-3-methylene-8-azabicyclo[3.2.1]octane; 3-Methylene-8-methyl-8-azabicyclo[3.2.1]octane; 8-Azabicyclo[3.2.1]octane, 8-methyl-3-methylene-; 8-Methyl-3-methylidene-8-azabicyclo[3.2.1]octane; Tropane, 3-methylene-8-methyl-; 3-Methylenetropane; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 8-Methyl-3-Methylene-8-Aza-Bicyclo[3.2.1]Octane is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and synthesis. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated development pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC/HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.