Description

1,2-Dihydroxy-3,4-epoxy-1,2,3,4-tetrahydro-6-methylchrysene is a complex polycyclic aromatic hydrocarbon derivative of significant interest in advanced organic synthesis and research. This compound serves as a critical synthetic intermediate and a model substrate for studying metabolic activation pathways and DNA adduct formation. It is primarily utilized by research institutions and industrial R&D laboratories focused on toxicology studies, environmental chemistry, and the development of analytical standards for polyaromatic hydrocarbon (PAH) metabolites.

Application

• Biochemical Research: Used as a reference standard and metabolite model in studies of polycyclic aromatic hydrocarbon (PAH) activation and carcinogenicity.
• Toxicology & Environmental Science: Employed in the investigation of DNA damage mechanisms and the biological impact of environmental pollutants.
• Organic Synthesis: Serves as a sophisticated building block for the synthesis of more complex PAH derivatives and labeled compounds.
• Analytical Chemistry: Utilized as a high-purity calibrant and standard in chromatographic (HPLC, GC-MS) methods for detecting and quantifying PAH metabolites.
• Pharmaceutical Research: Acts as a tool compound in early-stage discovery for understanding metabolic pathways relevant to drug safety.

Basic Information

Product Name	1,2-Dihydroxy-3,4-Epoxy-1,2,3,4-Tetrahydro-6-Methylchrysene
CAS No.	99762-88-6
Molecular Formula	C₁₉H₁₆O₃
Molecular Weight	292.33 g/mol
Synonyms	6-Methylchrysene-1,2-diol-3,4-epoxide; 1,2-Dihydroxy-3,4-epoxy-1,2,3,4-tetrahydro-6-methylchrysene; 6-Methylchrysene 1,2-dihydrodiol 3,4-epoxide; anti-6-Methylchrysene-1,2-diol-3,4-epoxide; PAH Metabolite Standard; 6-Methylchrysene diol epoxide
EINECS	Contact for details

Quality Control

Our production of this advanced chemical intermediate adheres to strict quality protocols to ensure batch-to-batch consistency and reliability for research applications. Identity and purity are confirmed through a combination of chromatographic and spectroscopic techniques, including HPLC and NMR. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and identification data is provided with each shipment to support your research integrity and documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) to minimize oxidation and degradation. Keep the container in a dry, cool, and well-ventilated area away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light tan solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.