Description

5-Bromo-2-Fluorobenzylamine Hydrochloride is a high-purity, halogenated benzylamine derivative primarily utilized as a critical building block in advanced organic synthesis. Its value lies in its bifunctional reactivity, offering both a nucleophilic amine group and a halogenated aromatic ring for subsequent cross-coupling and functionalization reactions. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, especially in kinase inhibitor and CNS-active molecule research.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, leveraging its halogenated aromatic structure.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic electronic materials.
• Chemical Biology Probes: Acts as a starting material for synthesizing fluorescent tags and molecular probes for biochemical assays.
• Custom Synthesis and Contract Manufacturing: A fundamental building block for custom chemical synthesis services targeting complex molecule production.

Basic Information

Product Name	5-Bromo-2-Fluorobenzylamine Hydrochloride
CAS No.	99725-13-0
Molecular Formula	C7H8BrClFN
Molecular Weight	240.50 g/mol
Synonyms	(5-Bromo-2-fluorophenyl)methanamine hydrochloride; 1-(5-Bromo-2-fluorophenyl)methanamine hydrochloride; 5-Bromo-2-fluoro-benzenemethanamine hydrochloride; 2-Fluoro-5-bromobenzylamine hydrochloride; α-Amino-5-bromo-2-fluorotoluene hydrochloride; Benzenemethanamine, 5-bromo-2-fluoro-, hydrochloride; 99725-13-0
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Fluorobenzylamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and consistency for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.