Description

5-Bromo-1H-Quinolin-2-One is a versatile brominated quinolinone derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its value lies in providing a functionalized scaffold for constructing complex molecules, particularly in pharmaceutical research and development. This high-purity building block is essential for medicinal chemists and R&D teams in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop new active compounds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, leveraging its heterocyclic structure for biological activity.
• Material Science Precursor: Serves as a starting material for creating specialized organic ligands, dyes, and photoactive compounds.
• Academic & R&D Laboratories: Employed in methodological studies and as a reference standard in organic synthesis and heterocyclic chemistry research.
• Fine Chemical Synthesis: Integral for constructing complex quinoline-based structures used in flavors, fragrances, and advanced chemical products.

Basic Information

Product Name	5-Bromo-1H-Quinolin-2-One
CAS No.	99465-09-5
Molecular Formula	C9H6BrNO
Molecular Weight	224.06 g/mol
Synonyms	5-Bromoquinolin-2(1H)-one; 5-Bromo-2-hydroxyquinoline; 5-Bromo-2-quinolone; 5-Bromo-1H-quinolin-2-ol; 2-Hydroxy-5-bromoquinoline; 5-Bromo-2(1H)-quinolinone; 5-Bromocarbostyril
EINECS	Contact for details

Quality Control

Our 5-Bromo-1H-Quinolin-2-One is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A Certificate of Analysis (COA) detailing all test results is provided with every shipment. We adhere to cGMP principles where applicable to support our clients in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.