Description

6-Bromo-8-Methylquinolin-2(1H)-One is a high-purity, synthetically valuable brominated quinolinone derivative. This compound serves as a crucial advanced pharmaceutical intermediate and a versatile building block in organic synthesis for the development of novel active compounds. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific bromine and quinolinone functionalities into their molecular targets.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting neurological disorders, oncology, and infectious diseases.
• Agrochemical Research: Used as a building block for developing new herbicides, fungicides, and insecticides with novel modes of action.
• Material Science: Serves as a monomer or functional unit in the creation of organic electronic materials, such as OLEDs and conductive polymers.
• Ligand Synthesis: Employed in the preparation of complex ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probe Development: Utilized to create molecular probes for studying enzyme function and biological pathways.
• Academic & Contract Research: Essential for fundamental organic chemistry research and custom synthesis projects in CROs and universities.

Basic Information

Product Name	6-Bromo-8-Methylquinolin-2(1H)-One
CAS No.	99465-08-4
Molecular Formula	C₁₀H₈BrNO
Molecular Weight	238.08 g/mol
Synonyms	6-Bromo-8-methyl-1,2-dihydroquinolin-2-one; 6-Bromo-8-methyl-2(1H)-quinolinone; 6-Bromo-8-methylquinolin-2-ol; 2-Hydroxy-6-bromo-8-methylquinoline; 8-Methyl-6-bromoquinolin-2(1H)-one; 99465-08-4; 6-Bromo-8-methyl-2-quinolone
EINECS	Contact for details

Quality Control

Our 6-Bromo-8-Methylquinolin-2(1H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment to guarantee batch-to-batch consistency and traceability for your R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep the container tightly sealed to minimize contact with atmospheric moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.