Description

6-Bromo-2-Hydroxy-Quinoline-3-Carboxylic Acid is a versatile brominated quinoline derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its value lies in the strategic positioning of functional groups—bromo, hydroxy, and carboxylic acid—which enable precise molecular construction for complex target molecules. This high-purity building block is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors, particularly for developing novel active ingredients and fine-tuning molecular properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially those targeting neurological disorders, cancers, and infectious diseases.
• Agrochemical Research: Used in developing novel herbicides, fungicides, and insecticides, leveraging the quinoline scaffold's bioactivity.
• Material Science: Serves as a monomer or functional additive in the creation of specialty polymers, dyes, and advanced organic electronic materials.
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and as a chelating ligand precursor in catalysis.
• Analytical Reference Standard: Utilized as a high-purity standard in quality control and method development for analytical laboratories.

Basic Information

Product Name	6-Bromo-2-Hydroxy-Quinoline-3-Carboxylic Acid
CAS No.	99465-06-2
Molecular Formula	C₁₁H₆BrNO₃
Molecular Weight	280.07 g/mol
Synonyms	6-Bromo-2-hydroxyquinoline-3-carboxylic acid; 2-Hydroxy-6-bromoquinoline-3-carboxylic acid; 3-Quinolinecarboxylic acid, 6-bromo-2-hydroxy-; 6-Bromo-2-oxo-1,2-dihydroquinoline-3-carboxylic acid; 6-Bromocarbostyril-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 6-Bromo-2-Hydroxy-Quinoline-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for research and commercial synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.