Description

6-Bromoquinoline-2-Chloro-3-Carbonitrile is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound matters for its unique halogenated and nitrile-substituted quinoline structure, enabling precise molecular construction in complex chemical pathways. It is primarily needed by researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly in developing kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used to construct complex heterocyclic scaffolds for new-generation herbicides, fungicides, and insecticides.
• Material Science: Acts as a building block for creating organic semiconductors, liquid crystals, and photoactive materials.
• Chemical Synthesis: A versatile reagent for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic substitution reactions due to its reactive bromo and chloro substituents.
• Academic & R&D: Employed in university and corporate research laboratories for methodological studies and exploring new chemical spaces in heterocyclic chemistry.

Basic Information

Product Name	6-Bromoquinoline-2-Chloro-3-Carbonitrile
CAS No.	99465-04-0
Molecular Formula	C10H4BrClN2
Molecular Weight	267.51 g/mol
Synonyms	2-Chloro-6-bromoquinoline-3-carbonitrile; 6-Bromo-2-chloroquinoline-3-carbonitrile; 3-Cyano-6-bromo-2-chloroquinoline; Quinoline, 6-bromo-2-chloro-3-cyano-; 99465-04-0; 6-Bromo-2-chloro-3-quinolinecarbonitrile
EINECS	Contact for details

Quality Control

Our 6-Bromoquinoline-2-Chloro-3-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment ensures the material meets the high standards required for research and commercial scale-up.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). The compound may be light-sensitive and should be handled accordingly.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.