Description

6-(Iodomethyl)-Quinoline is a versatile halogenated quinoline derivative, a key synthetic intermediate prized for its reactive iodomethyl functional group. This compound matters for enabling precise chemical modifications in complex molecule construction, offering a strategic handle for cross-coupling and alkylation reactions. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for developing new active ingredients and functional compounds.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of novel drug candidates, particularly in constructing quinoline-based pharmacophores for antimicrobial, anticancer, and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, where the quinoline scaffold can contribute to biological activity.
• Ligand and Catalyst Precursor: Acts as a starting material for the preparation of specialized ligands used in transition metal catalysis and organometallic chemistry.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers or light-emitting components, due to the tunable electronic properties of the quinoline core.
• Chemical Biology Probe Development: Utilized to create tagged or modified biomolecules for studying biological processes and target engagement.
• Custom Synthesis and Contract Manufacturing: A valuable intermediate for fine chemical producers engaged in custom synthesis projects for clients in various high-tech industries.

Basic Information

Product Name	6-(Iodomethyl)-Quinoline
CAS No.	99361-10-1
Molecular Formula	C₁₀H₈IN
Molecular Weight	269.08 g/mol
Synonyms	Quinoline, 6-(iodomethyl)-; 6-(Iodomethyl)quinoline; 6-Quinolinemethanol, iodo-; (6-Quinolylmethyl) iodide; 99361-10-1; Iodomethylquinoline
EINECS	Contact for details

Quality Control

Our 6-(Iodomethyl)-Quinoline is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay purity and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging are performed under controlled lighting conditions to maintain product integrity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.