Description

2-Ethynyl-4-Methoxy-Phenol is a versatile phenolic building block characterized by its ethynyl and methoxy functional groups. This compound is of significant commercial interest for its role as a key intermediate in the synthesis of complex organic molecules, particularly in pharmaceutical and advanced material research. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders or possessing specific receptor-binding profiles.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators, leveraging its phenolic core for bioactivity.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of advanced polymers, resins, and conductive materials due to the reactive ethynyl group.
• Ligand and Catalyst Development: Employed in organometallic chemistry to create specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Fine Chemical Production: Acts as a precursor for dyes, pigments, and other high-value specialty chemicals requiring a substituted phenol structure.

Basic Information

Product Name	2-Ethynyl-4-Methoxy-Phenol
CAS No.	99299-73-7
Molecular Formula	C9H8O2
Molecular Weight	148.16 g/mol
Synonyms	4-Methoxy-2-ethynylphenol; 2-Ethynyl-4-methoxyphenol; 2-Ethynyl-4-hydroxyanisole; 4-Methoxy-2-(ethynyl)phenol; 2-Ethynylguaiacol; Phenol, 2-ethynyl-4-methoxy-; 4-Methoxy-2-ethynyl-phenol
EINECS	Contact for details

Quality Control

Our 2-Ethynyl-4-Methoxy-Phenol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee it meets your specific R&D or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.