Description

Mannose 6-Sulfate is a sulfated monosaccharide derivative of D-mannose, a key building block in glycobiology and carbohydrate chemistry. This compound is valued for its role as a biochemical tool and a potential precursor in the synthesis of complex glycans and heparin analogs. It serves critical functions in research and development for pharmaceutical, diagnostic, and life science industries, particularly in studies involving carbohydrate-protein interactions, enzyme inhibition, and metabolic pathway analysis. Its specific sulfation pattern makes it a compound of significant interest for advanced therapeutic and diagnostic applications.

Application

• Biochemical Research: Used as a standard, substrate, or inhibitor in enzymatic studies, particularly for sulfatases and kinases involved in carbohydrate metabolism.
• Pharmaceutical Development: Serves as a key intermediate or building block in the synthesis of novel glycosaminoglycan (GAG) mimetics and heparin-like compounds for drug discovery.
• Glycobiology Studies: Essential for investigating carbohydrate-mediated cell signaling, pathogen recognition, and other biological processes dependent on sulfated sugars.
• Diagnostic Reagent Manufacturing: Employed in the formulation of assay kits and diagnostic tools for detecting specific enzyme activities or metabolic disorders.
• Life Science Tools: Incorporated into matrices for affinity chromatography or used to functionalize surfaces for studying protein-carbohydrate binding.
• Academic Research: A vital reagent for universities and research institutes focusing on metabolic engineering, synthetic biology, and structural biology of carbohydrates.

Basic Information

Item	Detail
Product Name	Mannose 6-Sulfate
CAS No.	99217-62-6
Molecular Formula	C6H12O9S
Molecular Weight	260.22 g/mol
Synonyms	D-Mannose 6-Sulfate; Mannose-6-SO4; 6-O-Sulfo-D-mannose; D-Mannose 6-(Hydrogen Sulfate); 6-Sulfomannose; (2S,3S,4S,5S,6R)-6-(Hydroxymethyl)-2,3,4,5-tetrahydroxyoxane-2-carboxylic acid 6-sulfate; Mannose 6-Sulphate
EINECS	Contact for details

Quality Control

Every batch of Mannose 6-Sulfate is manufactured and tested under a strict quality management system. We provide comprehensive analytical documentation to ensure product identity, purity, and consistency for your research and development needs. A Certificate of Analysis (COA) detailing specific batch results for purity, identity, and impurities is available for every shipment. Our quality commitment supports compliance with relevant standards for research-grade biochemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and prevent degradation. For long-term storage, consider using desiccant packs in the container.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.5%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.