Description

2-[[(2R)-2-Acetamido-3-Methyl-Butanoyl]-Nitroso-Amino]Acetic Acid is a specialized chiral intermediate featuring a nitrosoamino functional group. This compound is valued for its role in the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily sought by fine chemical manufacturers and R&D laboratories working on novel therapeutic agents, peptide mimetics, and advanced organic synthesis.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), especially those with chiral centers.
• Peptidomimetic Research: Used in the design and development of peptide analogs and enzyme inhibitors.
• Organic Synthesis Reagent: Serves as a precursor for introducing nitrosoamino and acetamido functionalities into target molecules.
• Bioconjugation Chemistry: Potential use in creating specialized linkers for bioconjugation applications in drug delivery systems.
• Academic & Industrial R&D: Employed in chemical research for methodological studies and the exploration of new synthetic pathways.

Basic Information

Product Name	2-[[(2R)-2-Acetamido-3-Methyl-Butanoyl]-Nitroso-Amino]Acetic Acid
CAS No.	99152-10-0
Molecular Formula	C10H17N3O5
Molecular Weight	259.26 g/mol
Synonyms	N-[(2R)-2-Acetamido-3-methylbutanoyl]-N-nitrosoglycine; (2R)-2-Acetamido-3-methyl-N-(nitrosocarbamoylmethyl)butanamide; N-Nitroso-N-[(2R)-2-acetamido-3-methylbutanoyl]glycine; L-Valine, N-acetyl-N-nitroso-, glycine derivative; Ac-DL-Val-NNO-Gly-OH (stereospecific form); Nitrosoamino acetic acid valine derivative
EINECS	Contact for details

Quality Control

Our 2-[[(2R)-2-Acetamido-3-Methyl-Butanoyl]-Nitroso-Amino]Acetic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity verification and impurity profiling, to ensure it meets the high standards required for research and synthesis. A Certificate of Analysis (COA) detailing specifications such as assay, enantiomeric excess, and related substances is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store the product under an inert atmosphere for long-term preservation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 98.0% ee
Loss on Drying	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.