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(E)-Ethyl 3-(2-Bromophenyl)Acrylate CAS NO 99134-25-5


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CAS No.:99134-25-5

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

(E)-Ethyl 3-(2-Bromophenyl)Acrylate is a high-purity, versatile acrylate ester building block characterized by its brominated aromatic ring and α,β-unsaturated ester functionality. This compound is essential for advanced organic synthesis, particularly in constructing complex molecular architectures via cross-coupling and cycloaddition reactions. It is primarily sought after by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and advanced materials sectors for developing novel active ingredients and functional polymers.

Application

  • Pharmaceutical Intermediate: A key synthon for the preparation of drug candidates, especially those targeting central nervous system (CNS) disorders and inflammatory diseases.
  • Agrochemical Synthesis: Used in the research and development of new-generation herbicides and fungicides, leveraging the bromophenyl moiety for bioactivity.
  • Material Science Research: Serves as a monomer or cross-linker precursor in the development of specialty polymers with tailored optical or electronic properties.
  • Organic Synthesis Building Block: Employed in Heck reactions, Suzuki-Miyaura cross-couplings, and Diels-Alder reactions to introduce the 2-bromophenylacryloyl group.
  • Liquid Crystal & OLED Materials: Investigated as a core component in the synthesis of advanced organic semiconductors and liquid crystal displays (LCDs).
  • Chemical Biology Probes: Utilized to create tagged molecules for studying biological pathways and protein interactions.

Basic Information

Product Name (E)-Ethyl 3-(2-Bromophenyl)Acrylate
CAS No. 99134-25-5
Molecular Formula C11H11BrO2
Molecular Weight 255.11 g/mol
Synonyms Ethyl (E)-3-(2-Bromophenyl)-2-propenoate; trans-Ethyl 3-(2-Bromophenyl)acrylate; 2-Bromocinnamic Acid Ethyl Ester; (E)-Ethyl 3-(o-Bromophenyl)acrylate; Ethyl (E)-3-(2-Bromophenyl)acrylate; (E)-3-(2-Bromophenyl)acrylic Acid Ethyl Ester; NSC 405124; AI3-52066
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Quality Control

Every batch of (E)-Ethyl 3-(2-Bromophenyl)Acrylate is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and consistency for your critical research and development projects. Certificates of Analysis (COA) detailing purity by HPLC, identity confirmation by NMR and IR, and impurity profiles are available for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its nature as a strong acid/organic solvent and highly volatile compound, keep away from heat, sparks, and open flames. Ensure containers are kept tightly sealed when not in use to prevent evaporation and moisture absorption.

Specification

Item Specification
Appearance Colorless to pale yellow clear liquid
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 97.0% (Area %)
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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