Description

2H-Benzimidazol-2-One,5-Chloro-1,3-Dihydro-,Hydrazone(9Ci) is a specialized heterocyclic organic compound that serves as a valuable chemical intermediate and building block in advanced synthesis. Its unique structure, featuring both benzimidazole and hydrazone functionalities, makes it a critical precursor for developing active pharmaceutical ingredients (APIs) and high-performance materials. This compound is primarily sought by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel molecules with targeted properties. CAS number 99122-11-9.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel benzimidazole-derived APIs, particularly for antiviral, antimicrobial, and anticancer research candidates.
• Agrochemical Synthesis: Used as a precursor in developing advanced fungicides, herbicides, and plant growth regulators that leverage the chlorinated benzimidazole scaffold.
• Organic Light-Emitting Diodes (OLEDs): Serves as a starting material for synthesizing electron-transport or emissive layer materials in electronic displays and lighting.
• Coordination Chemistry & Ligand Synthesis: The hydrazone moiety acts as a versatile chelating ligand for constructing metal-organic frameworks (MOFs) and catalysts.
• Dye & Pigment Manufacturing: Intermediate for producing specialized heterocyclic dyes with enhanced light-fastness and color properties.
• Polymer Science: Incorporated as a monomer or additive to impart thermal stability and specific functional groups into high-performance polymers.
• Analytical Chemistry: Used as a derivatization agent or a standard in chromatographic methods for detecting similar structural compounds.
• Academic & Contract Research: Essential reagent for medicinal chemistry programs and structure-activity relationship (SAR) studies in university and CRO laboratories.

Basic Information

Product Name	2H-Benzimidazol-2-One,5-Chloro-1,3-Dihydro-,Hydrazone(9Ci)
CAS No.	99122-11-9
Molecular Formula	C7H5ClN4O
Molecular Weight	196.59 g/mol
Synonyms	5-Chloro-1,3-dihydro-2H-benzimidazol-2-one hydrazone; 5-Chloro-2-benzimidazolinone hydrazone; 5-Chloro-2-hydroxybenzimidazole hydrazone; 5-Chloro-2-oxo-1H-benzimidazole-1(2H)-carbohydrazonamide; 99122-11-9; Hydrazone of 5-Chloro-2-benzimidazolinone; N-(5-Chloro-2-oxo-2,3-dihydro-1H-benzimidazol-1-yl)formimidamide
EINECS	Contact for details

Quality Control

Our production of 2H-Benzimidazol-2-One,5-Chloro-1,3-Dihydro-,Hydrazone(9Ci) adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity assessment, IR and NMR for structural confirmation, and precise determination of residual solvents and moisture content. Certificates of Analysis (COA) documenting all test results are provided with every shipment. We support cGMP compliance for pharmaceutical applications and can tailor specifications to meet the requirements of USP, EP, or other relevant pharmacopeial standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is easily oxidized and should be stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flames. Isolate from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.