Description

6-Bromo-1-Methyl-2,3-Dihydroquinolin-4-One is a versatile brominated heterocyclic building block of significant interest in advanced organic synthesis. Its core quinolinone scaffold, functionalized with a bromine atom, makes it a critical intermediate for constructing complex molecular architectures. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and kinase inhibitors.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, leveraging its heterocyclic structure for bioactivity.
• Material Science: Acts as a building block for organic semiconductors, liquid crystals, and advanced polymers due to its electron-rich aromatic system.
• Chemical Biology: Employed in the design and synthesis of molecular probes and fluorescent tags for studying biological processes.
• Academic & R&D: A valuable reagent for methodological studies in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and other transition metal-catalyzed transformations.
• Fine Chemical Synthesis: Used in the multi-step synthesis of complex natural product analogs and specialty chemicals.

Basic Information

Product Name	6-Bromo-1-Methyl-2,3-Dihydroquinolin-4-One
CAS No.	99057-84-8
Molecular Formula	C10H8BrNO
Molecular Weight	238.08 g/mol
Synonyms	6-Bromo-1-methyl-1,2-dihydro-4(3H)-quinolinone; 6-Bromo-1-methyl-3,4-dihydro-2(1H)-quinolinone; 6-Bromo-1-methyl-2,3-dihydroquinolin-4(1H)-one; 1-Methyl-6-bromo-2,3-dihydro-4(1H)-quinolinone; 4(1H)-Quinolinone, 6-bromo-1,2-dihydro-1-methyl-; 99057-84-8; 6-Bromo-1-methyl-3,4-dihydroquinolin-2(1H)-one
EINECS	Contact for details

Quality Control

Our 6-Bromo-1-Methyl-2,3-Dihydroquinolin-4-One is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment to ensure traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.