Description

4-Chloro-1-(2-Methylpropyl)-1H-Imidazo[4,5-C]Quinoline is a high-purity, advanced pharmaceutical intermediate belonging to the imidazoquinoline class of heterocyclic compounds. This compound is of significant commercial importance due to its role as a key synthetic precursor in the development of novel therapeutic agents, particularly in immunology and antiviral research. It is primarily sought by R&D laboratories, fine chemical manufacturers, and pharmaceutical companies engaged in the synthesis of complex active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of Toll-like receptor (TLR) agonists and other immunomodulatory drug candidates.
• Antiviral Research: Used in the development of novel compounds targeting viral infections.
• Medicinal Chemistry R&D: Serves as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex, high-value specialty chemicals.
• Biochemical Research: Utilized as a tool compound to study immune response pathways and signaling mechanisms.

Basic Information

Product Name	4-Chloro-1-(2-Methylpropyl)-1H-Imidazo[4,5-C]Quinoline
CAS No.	99010-64-7
Molecular Formula	C14H14ClN3
Molecular Weight	259.73 g/mol
Synonyms	4-Chloro-1-isobutyl-1H-imidazo[4,5-c]quinoline; 1-Isobutyl-4-chloro-1H-imidazo[4,5-c]quinoline; CL-097; Imiquimod Impurity; TLR7/8 Agonist Intermediate; 99010-64-7; 4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline
EINECS	Contact for details

Quality Control

Our 4-Chloro-1-(2-Methylpropyl)-1H-Imidazo[4,5-C]Quinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, confirming compliance with client specifications and cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.