Description

2-Iodo-1-Methoxy-3-Nitro-Benzene is a versatile halogenated aromatic building block of significant interest in advanced organic synthesis. Its unique structure, featuring iodine, methoxy, and nitro substituents, makes it a critical intermediate for constructing complex molecules. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in cross-coupling reactions and the synthesis of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those requiring halogenated aromatic cores for further functionalization via Suzuki, Stille, or other cross-coupling reactions.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides where the iodine atom serves as a reactive handle for creating diverse chemical libraries.
• Material Science Research: Employed in the development of organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, where its electron-withdrawing nitro group can tune electronic properties.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in homogeneous catalysis and metal-organic frameworks (MOFs).
• Dye and Pigment Intermediate: Acts as a building block in the synthesis of specialized azo dyes and nitro-aromatic based colorants.
• Academic & R&D Laboratories: A valuable reagent for methodological studies in organic chemistry, including novel halogenation and functional group transformation protocols.

Basic Information

Product Name	2-Iodo-1-Methoxy-3-Nitro-Benzene
CAS No.	98991-08-3
Molecular Formula	C7H6INO3
Molecular Weight	279.03 g/mol
Synonyms	1-Iodo-2-Methoxy-5-Nitrobenzene; 2-Iodoanisole-5-Nitro; 5-Nitro-2-iodoanisole; 2-Methoxy-5-nitroiodobenzene; 5-Nitro-2-iodomethoxybenzene; 1-Methoxy-2-iodo-5-nitrobenzene; 2-Iodo-5-nitroanisole
EINECS	Contact for details

Quality Control

Every batch of 2-Iodo-1-Methoxy-3-Nitro-Benzene is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive synthetic applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.