Description

n-Acetylglucosyl--2-Mannosyl--3-Mannosyl--4-Glucosyl--1-Ceramide is a complex glycosphingolipid, a key structural component of cell membranes with significant biological signaling functions. This high-purity compound is essential for advanced research in glycobiology and the development of novel therapeutic and diagnostic agents. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors for studying cell-cell recognition, immune response modulation, and as a reference standard.

Application

• Biomedical Research: Critical reagent for studying glycosphingolipid metabolism, cell signaling pathways, and membrane biology.
• Pharmaceutical Development: Serves as a reference standard and a potential starting material or intermediate for the synthesis of novel glycotherapeutic agents.
• Diagnostic Assays: Used in the development of immunoassays and diagnostic kits targeting specific glycolipid antigens.
• Enzymology Studies: Substrate for research on glycosyltransferases, glycosidases, and other enzymes involved in glycolipid biosynthesis and degradation.
• Cell Culture & Immunology: Investigated for its role in modulating immune cell function and as a component in specialized cell culture media.
• Standards & Calibration: High-purity material for use as an analytical standard in HPLC, MS, and NMR for quality control and method validation.

Basic Information

Product Name	n-Acetylglucosyl--2-Mannosyl--3-Mannosyl--4-Glucosyl--1-Ceramide
CAS No.	98824-96-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	GlcNAcβ1-2Manα1-3Manβ1-4Glcβ1-1'Cer; IV2-β-GlcNAc-GgOse4Cer; nAcGM1; Asialo-GM2; GgOse4Cer with β-GlcNAc at terminal Gal; Glycosphingolipid Gg4; Globoside with terminal N-acetylglucosamine
EINECS	Contact for details

Quality Control

Every batch of n-Acetylglucosyl--2-Mannosyl--3-Mannosyl--4-Glucosyl--1-Ceramide is produced and analyzed under strict quality management protocols. Our products undergo rigorous purity and identity testing using advanced analytical techniques to ensure consistency and compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and hydrolysis.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Solvent Residue (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.