Description

n-(1,3,4,6,7,12B-Hexahydro-2H-Benzo(B)Furo(2,3-A)Quinolizin-2-Yl)-n-Methyl-2-Hydroxyethanesulfonamide CAS NO 98612-56-7 is a complex, high-purity heterocyclic sulfonamide derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical building block or key intermediate for synthesizing novel therapeutic agents, particularly those targeting the central nervous system. It is primarily sought by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the discovery of new drugs.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of potential drug candidates, especially for neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used as a core scaffold or a functionalized fragment in structure-activity relationship (SAR) studies and lead optimization programs.
• Biochemical Tool Compound: Employed in in vitro assays to study specific biological pathways or protein interactions relevant to disease mechanisms.
• Reference Standard: Serves as a high-purity analytical standard for method development, quality control, and regulatory submissions in drug development pipelines.
• Custom Synthesis Building Block: Utilized by fine chemical suppliers for the contract manufacturing of specialized, non-commercial compounds for client research.

Basic Information

Product Name	n-(1,3,4,6,7,12B-Hexahydro-2H-Benzo(B)Furo(2,3-A)Quinolizin-2-Yl)-n-Methyl-2-Hydroxyethanesulfonamide
CAS No.	98612-56-7
Molecular Formula	C19H24N2O4S
Molecular Weight	376.47 g/mol
Synonyms	2-Hydroxy-N-methyl-N-[(1R,12bS)-1,3,4,6,7,12b-hexahydro-2H-benzo[b]furo[2,3-a]quinolizin-2-yl]ethanesulfonamide; 2-Hydroxy-N-methyl-N-(1,3,4,6,7,12b-hexahydro-2H-benzo[b]furo[2,3-a]quinolizin-2-yl)ethanesulfonamide; Benzo[b]furo[2,3-a]quinolizine-2-ethanesulfonamide derivative; NSC 339586; L-741,742 (related analog series); Potential Dopamine D4 Receptor Ligand Intermediate
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency for research applications. Quality is verified through a comprehensive suite of analytical techniques including HPLC, NMR, and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting purity, identity, and impurity profiles. We support development efforts with custom purity grades and analytical data packages tailored to your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.