Description

2-(tert-Butoxycarbonylamino)-1,2,3,4-Tetrahydronaphthalene-2-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its tetralin core and protected amine functionality. This compound matters as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), enabling precise molecular construction. It is primarily needed by research institutions and manufacturers in the pharmaceutical and biotechnology sectors for developing new therapeutic agents, particularly in central nervous system (CNS) and cardiovascular research.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel Active Pharmaceutical Ingredients (APIs).
• Peptidomimetic Chemistry: Used in the design and synthesis of peptide analogs and conformationally constrained scaffolds for drug discovery.
• Medicinal Chemistry Research: Serves as a versatile building block for constructing fused-ring systems and exploring structure-activity relationships (SAR).
• Process Chemistry: Employed in route scouting and scale-up synthesis for preclinical and clinical trial material production.
• Bioconjugation: The carboxylic acid group allows for coupling reactions to create targeted molecular probes or drug-linker complexes.
• Academic & Contract Research: Utilized in academic laboratories and CROs (Contract Research Organizations) for synthetic methodology development.

Basic Information

Product Name	2-(tert-Butoxycarbonylamino)-1,2,3,4-Tetrahydronaphthalene-2-Carboxylic Acid
CAS No.	98569-12-1
Molecular Formula	C₁₆H₂₁NO₄
Molecular Weight	291.34 g/mol
Synonyms	Boc-1,2,3,4-Tetrahydro-2-naphthylglycine; 2-[(tert-Butoxycarbonyl)amino]-1,2,3,4-tetrahydronaphthalene-2-carboxylic acid; Boc-Amino-tetralin-2-carboxylic Acid; N-Boc-2-amino-1,2,3,4-tetrahydronaphthalene-2-carboxylic acid; 2-(Boc-amino)-1,2,3,4-tetrahydronaphthalene-2-carboxylic acid; 2-[[(1,1-Dimethylethoxy)carbonyl]amino]-1,2,3,4-tetrahydro-2-naphthalenecarboxylic acid; (2S)-2-[(tert-Butoxycarbonyl)amino]-1,2,3,4-tetrahydronaphthalene-2-carboxylic acid (for chiral form); Tetralin-Boc-Amino Acid
EINECS	Contact for details

Quality Control

Our 2-(tert-Butoxycarbonylamino)-1,2,3,4-Tetrahydronaphthalene-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and under dry conditions to prevent degradation. For long-term storage, consider inert atmosphere packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Specific Rotation (if chiral)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.