Description

Glucuronic Acid 2-Sulfate is a key sulfated monosaccharide derivative, playing a crucial role in the biosynthesis and structural integrity of complex glycosaminoglycans (GAGs). This high-purity biochemical is essential for research and development in advanced life science applications, where precise molecular structure and activity are paramount. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostic reagent sectors for studying metabolic pathways, enzyme substrates, and as a reference standard.

Application

• Biochemical Research & Reference Standard: Serves as a critical reference compound and substrate for enzymatic studies, particularly in glucuronosyltransferase and sulfatase research.
• Glycosaminoglycan (GAG) Synthesis Studies: Used in the investigation of heparin, heparan sulfate, and other sulfated polysaccharide biosynthesis pathways.
• Pharmaceutical Intermediate: Acts as a potential building block or intermediate in the development of novel therapeutic agents targeting carbohydrate-mediated processes.
• Diagnostic Reagent Development: Employed in the formulation of assay kits and diagnostic tools for detecting specific metabolic disorders or enzyme deficiencies.
• Cell Biology & Signal Transduction: Utilized in studies exploring the role of sulfated sugars in cell signaling, adhesion, and extracellular matrix interactions.

Basic Information

Product Name	Glucuronic Acid 2-Sulfate
CAS No.	98517-62-5
Molecular Formula	C6H10O11S
Molecular Weight	290.20 g/mol
Synonyms	2-O-Sulfo-D-glucuronic acid; D-Glucuronic acid 2-sulfate; 2-Sulfo-D-glucuronic acid; Glucuronic acid 2-(hydrogen sulfate); (2S,3S,4S,5R)-2,3,4,5-Tetrahydroxy-6-oxohexyl hydrogen sulfate; UDP-glucuronic acid 2-sulfate (related precursor); Glycosaminoglycan precursor sulfate
EINECS	Contact for details

Quality Control

Our Glucuronic Acid 2-Sulfate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, NMR for structural confirmation, and mass spectrometry to ensure identity and meet stringent research-grade specifications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, cool place. This product is hygroscopic (moisture-sensitive). For long-term storage, desiccate and keep under inert atmosphere if possible. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.