Description

1-[(6-Aminohexyl)Sulfanyl]Ethan-1-One Hydrochloride is a specialized organic intermediate featuring a terminal amine group protected as a hydrochloride salt and a thioester linkage. This unique bifunctional structure makes it a valuable building block for the synthesis of complex molecules, particularly in pharmaceutical and bioconjugation chemistry. It is primarily sought after by research institutions and manufacturers in the life sciences sector for developing targeted drug delivery systems, diagnostic agents, and novel therapeutic compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for drugs requiring targeted delivery or specific linker chemistry.
• Bioconjugation Reagent: Used to covalently link bioactive molecules (e.g., peptides, antibodies, drugs) to carriers, nanoparticles, or surfaces via its reactive amine and thioester groups.
• Proteomics Research: Employed in the development of chemical probes and affinity tags for studying protein function, interactions, and localization.
• Polymer Modification: Serves as a functional monomer or cross-linking agent for creating advanced polymers with amine-reactive sites for further customization.
• Diagnostic Agent Synthesis: Utilized in the production of contrast agents and molecular imaging probes for medical diagnostics.
• Chemical Biology Tool: Acts as a versatile scaffold for constructing compound libraries and exploring structure-activity relationships (SAR) in drug discovery.

Basic Information

Product Name	1-[(6-Aminohexyl)Sulfanyl]Ethan-1-One Hydrochloride
CAS No.	98486-87-4
Molecular Formula	C8H18ClNOS
Molecular Weight	211.75 g/mol
Synonyms	6-Acetylthiohexylamine Hydrochloride; N-(6-Mercaptohexyl)acetamide Hydrochloride; 1-(6-Aminohexylthio)ethanone Hydrochloride; S-(6-Aminohexyl) Thioacetate Hydrochloride; Acetyl-6-aminohexyl Sulfide Hydrochloride; 6-(Acetylthio)hexan-1-amine Hydrochloride; Aminohexyl Thioacetate Hydrochloride
EINECS	Contact for details

Quality Control

Our 1-[(6-Aminohexyl)Sulfanyl]Ethan-1-One Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and synthesis applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay, impurity profile, and physical characteristics.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.