Description

4-Chloro-6,8-Diiodoquinazoline is a halogenated quinazoline derivative, a versatile and highly functionalized heterocyclic building block. Its molecular structure, featuring both chloro and iodo substituents, makes it a critical intermediate for constructing complex molecules in advanced research and development. This compound is primarily sought after by pharmaceutical and agrochemical R&D teams for the synthesis of novel active ingredients, including kinase inhibitors and other biologically relevant compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of targeted small-molecule drugs, particularly kinase inhibitors for oncology and inflammatory diseases.
• Agrochemical Research: Used to develop new active ingredients for crop protection products, leveraging its halogenated quinazoline core.
• Chemical Biology Probe Development: Serves as a scaffold for creating tool compounds to study enzyme function and cellular pathways.
• Material Science Research: Potential building block for organic electronic materials and metal-organic frameworks (MOFs) due to its halogen atoms and planar structure.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research institutions for bespoke synthetic routes and library production.

Basic Information

Product Name	4-Chloro-6,8-Diiodoquinazoline
CAS No.	98436-53-4
Molecular Formula	C8H3ClI2N2
Molecular Weight	416.38 g/mol
Synonyms	4-Chloro-6,8-diiodoquinazoline; 6,8-Diiodo-4-chloroquinazoline; Quinazoline, 4-chloro-6,8-diiodo-; 98436-53-4; 4-Chlor-6,8-diiodchinazolin (German); 4-クロロ-6,8-ジヨードキナゾリン (Japanese)
EINECS	Contact for details

Quality Control

Our 4-Chloro-6,8-Diiodoquinazoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and elemental analysis. We provide detailed Certificates of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.