Description

1,3-Diazaspiro[4.4]Nonane-2,4-Dione,4-Thio-(6Ci) is a specialized spirocyclic thiouracil derivative, a high-value synthetic intermediate prized for its unique constrained molecular architecture. Its core value lies in serving as a sophisticated building block for the development of novel pharmaceuticals and advanced organic materials. This compound is essential for R&D and production chemists in the pharmaceutical, agrochemical, and material science industries seeking to incorporate complex heterocyclic motifs into new molecular entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, due to its spirocyclic scaffold which can mimic bioactive conformations.
• Agrochemical Research: Used in the development of new-generation herbicides and pesticides, where the thiocarbonyl and spirocyclic structure can contribute to unique modes of action.
• Material Science: Serves as a monomer or cross-linking agent in the synthesis of specialty polymers and organic electronic materials with tailored properties.
• Chemical Biology Probe Development: Employed in creating molecular probes and inhibitors for studying enzyme mechanisms and protein-ligand interactions.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) conducting fundamental research in heterocyclic and medicinal chemistry.

Basic Information

Item	Detail
Product Name	1,3-Diazaspiro[4.4]Nonane-2,4-Dione,4-Thio-(6Ci)
CAS No.	98334-44-2
Molecular Formula	C7H8N2O2S
Molecular Weight	184.22 g/mol
Synonyms	4-Thioxo-1,3-diazaspiro[4.4]nonane-2-one; 4-Thio-1,3-diazaspiro[4.4]nonane-2,4-dione; Spiro[4.4]nonane-2,4-dione, 1,3-diaza-4-thio-; 4-Thiospirohydantoin; 1,3-Diazaspiro[4.4]nonane-2,4-dione, 4-thio-; Thiospirohydantoin derivative
EINECS	Contact for details

Quality Control

Our 1,3-Diazaspiro[4.4]Nonane-2,4-Dione,4-Thio-(6Ci) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality parameters. Our commitment to cGMP principles and ISO-aligned processes guarantees a reliable supply of high-purity material for your most demanding applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed in a dry environment. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.