Description

Cytidine Monophosphate-n-Glycoloylneuraminic Acid is a key biochemical intermediate and activated sugar nucleotide donor. This compound is essential for the enzymatic synthesis and study of glycoloylneuraminic acid-containing glycoconjugates, which are of significant interest in glycobiology research. It is primarily utilized by research institutions and biotechnology companies focused on carbohydrate chemistry, vaccine development, and the study of cell surface interactions.

Application

• Enzymatic Glycosylation Substrate: Serves as a high-energy donor substrate for sialyltransferases in the in vitro synthesis of sialoglycoproteins and sialoglycolipids.
• Glycobiology Research: A critical tool for investigating the biosynthesis, structure, and function of glycoloylneuraminic acid (GcNeu), a sialic acid variant.
• Bioconjugate & Vaccine Development: Used in the chemoenzymatic preparation of neoglycoconjugates for immunological studies and potential vaccine candidates.
• Diagnostic Reagent Synthesis: Employed in the production of specialized reagents and probes for detecting specific carbohydrate epitopes.
• Metabolic Pathway Studies: Facilitates research into sialic acid metabolism and related disorders.
• Pharmaceutical Intermediate: Acts as a building block in the development of novel therapeutic agents targeting sialic acid-mediated processes.

Basic Information

Product Name	Cytidine Monophosphate-n-Glycoloylneuraminic Acid
CAS No.	98300-80-2
Molecular Formula	C20H31N4O17P
Molecular Weight	606.45 g/mol
Synonyms	CMP-GcNeu; CMP-N-Glycoloylneuraminate; Cytidine 5'-Monophosphate N-Glycoloyl-β-neuraminic Acid; CMP-N-Glycoloylneuraminic Acid; CMP-Glycoloylneuraminic Acid; CMP-Sialic Acid (Glycoloyl variant); Activated N-Glycoloylneuraminic Acid
EINECS	Contact for details

Quality Control

Our Cytidine Monophosphate-n-Glycoloylneuraminic Acid is produced under stringent quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the exacting standards required for advanced biochemical research. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive) and should be kept under desiccant in a dry environment. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder or lyophilized solid
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0 %
Biological Activity	Functional as donor substrate for relevant sialyltransferases

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.