Description

1-[(8-Methoxy-5-Quinolinyl)Sulfonyl]Aziridine is a specialized sulfonamide derivative featuring a quinoline core and an aziridine functional group. This compound is valued for its role as a key synthetic intermediate and building block in advanced organic synthesis, particularly for constructing complex nitrogen-containing heterocycles. It is primarily utilized by research institutions and pharmaceutical development companies engaged in medicinal chemistry and the synthesis of novel bioactive molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of potential drug candidates, especially those targeting specific enzyme pathways.
• Medicinal Chemistry Research: Used as a versatile building block for constructing novel heterocyclic libraries for high-throughput screening and structure-activity relationship (SAR) studies.
• Organic Synthesis Reagent: Functions as an electrophilic alkylating agent due to the reactive aziridine ring, enabling the introduction of functionalized amine groups into complex molecules.
• Agrochemical Development: Employed in the research and development of new pesticides and herbicides, leveraging its unique heterocyclic structure.
• Material Science Research: Investigated as a monomer or cross-linking agent for creating specialized polymers with tailored properties.

Basic Information

Product Name	1-[(8-Methoxy-5-Quinolinyl)Sulfonyl]Aziridine
CAS No.	98267-09-5
Molecular Formula	C₁₃H₁₂N₂O₃S
Molecular Weight	276.31 g/mol
Synonyms	8-Methoxy-5-quinolinesulfonyl aziridine; Aziridine, 1-[(8-methoxy-5-quinolinyl)sulfonyl]-; 5-(Aziridine-1-sulfonyl)-8-methoxyquinoline; N-(8-Methoxyquinolin-5-ylsulfonyl)aziridine; 1-(8-Methoxyquinoline-5-sulfonyl)aziridine; 8-Methoxy-N-(aziridin-1-ylsulfonyl)quinolin-5-amine
EINECS	Contact for details

Quality Control

Our production of 1-[(8-Methoxy-5-Quinolinyl)Sulfonyl]Aziridine adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity for research applications. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to the reactive aziridine moiety, handle and store separately from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.