Description

(-)-(1R,3R,4S)-Menthol CAS NO 98167-53-4 is a specific stereoisomer of menthol, a naturally occurring organic compound prized for its potent cooling and refreshing properties. This high-purity enantiomer is critical for applications requiring precise sensory profiles and consistent biological activity. It is an essential ingredient for the pharmaceutical, flavor and fragrance, and personal care industries, where its stereochemical purity directly impacts product efficacy and quality.

Application

• Pharmaceutical Actives: A key cooling agent and active ingredient in topical analgesics, cough drops, nasal decongestants, and oral care products.
• Flavor & Fragrance Formulation: Used to impart a clean, sharp minty character to confectionery, oral hygiene products, chewing gum, and fine fragrances.
• Personal Care & Cosmetics: Incorporated into skincare products, aftershaves, and balms for its immediate cooling sensation and soothing effect.
• Tobacco & E-liquids: Employed as a flavorant and cooling additive in cigarettes and vaping products.
• Chemical Synthesis: Serves as a chiral building block or starting material for the synthesis of more complex organic molecules in fine chemical production.
• Industrial Applications: Used in specialty industrial products where a cooling or refreshing effect is desired, such as in certain cleaning agents or air fresheners.

Basic Information

Product Name	(-)-(1R,3R,4S)-Menthol
CAS No.	98167-53-4
Molecular Formula	C₁₀H₂₀O
Molecular Weight	156.27 g/mol
Synonyms	L-Menthol; (-)-Menthol; (1R,2S,5R)-2-Isopropyl-5-methylcyclohexanol; Levomenthol; Peppermint Camphor; 3-p-Menthanol; Hexahydrothymol; Menthol, natural
EINECS	Contact for details

Quality Control

Our (-)-(1R,3R,4S)-Menthol is produced and tested under strict quality management systems. We offer grades compliant with relevant pharmacopeial standards (USP/EP/BP) and food-grade (FCC) specifications, ensuring suitability for sensitive applications. Every batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles. Our quality commitment ensures reliable supply and batch-to-batch consistency for our global partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area at controlled room temperature (15-25°C). Due to its highly volatile nature, ensure containers are sealed when not in use to prevent loss and maintain purity. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White crystalline solid or colorless crystals
Identification (IR)	Conforms to standard
Assay (HPLC)	≥ 99.0%
Enantiomeric Purity (GC/HPLC)	≥ 99.5%
Melting Point	42°C - 45°C
Specific Rotation [α]D20	-49° to -50°
Heavy Metals	≤ 10 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.