Description

Oxan-4-Yl 4-Methylbenzenesulfonate is a specialized organic sulfonate ester, a key building block in advanced chemical synthesis. This high-purity intermediate is valued for its role in introducing the oxan-4-yl (tetrahydropyran-4-yl) protecting group or moiety into target molecules. It is essential for researchers and process chemists in the pharmaceutical and agrochemical industries who require reliable, high-quality reagents for developing active ingredients and novel compounds.

Application

• Pharmaceutical Intermediate: A critical reagent in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing the tetrahydropyranyl group which can influence a drug's metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides where the oxan-4-yl group is a key structural component.
• Organic Synthesis Building Block: Serves as a versatile electrophile in nucleophilic substitution reactions for constructing complex molecular architectures in academic and industrial R&D settings.
• Protecting Group Chemistry: Specifically utilized as a reagent for the protection of alcohols and other functional groups in multi-step synthetic pathways.
• Material Science Research: Employed in the development of specialty polymers and advanced organic materials with tailored properties.

Basic Information

Product Name	Oxan-4-Yl 4-Methylbenzenesulfonate
CAS No.	97986-34-0
Molecular Formula	C₁₂H₁₆O₄S
Molecular Weight	256.32 g/mol
Synonyms	Tetrahydropyran-4-yl 4-methylbenzenesulfonate; 4-Methylbenzenesulfonic acid tetrahydropyran-4-yl ester; Oxan-4-yl tosylate; THP-OTs; Tetrahydropyran-4-yl tosylate; p-Toluenesulfonic acid tetrahydropyran-4-yl ester; 4-Toluenesulfonic acid oxan-4-yl ester
EINECS	Contact for details

Quality Control

Our Oxan-4-Yl 4-Methylbenzenesulfonate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.