Description

D-Tyrosine-Obzl p-Tosylate is a protected derivative of the non-essential amino acid tyrosine, specifically designed for advanced peptide synthesis and pharmaceutical research. This compound is critical for researchers and manufacturers requiring precise control over tyrosine's reactive side chain during complex chemical processes. It is primarily utilized in the development of peptide-based therapeutics, biochemical research, and as a key chiral building block in medicinal chemistry.

Application

• Peptide Synthesis: Serves as a crucial protected tyrosine residue in Solid-Phase Peptide Synthesis (SPPS) and solution-phase synthesis, preventing unwanted side reactions.
• Pharmaceutical Intermediates: Used as a high-purity chiral building block in the research and development of novel active pharmaceutical ingredients (APIs).
• Biochemical Research: Employed in studies of enzyme kinetics, protein structure-function relationships, and signal transduction pathways involving tyrosine phosphorylation.
• Proteomics & Labeling: Acts as a precursor for the synthesis of labeled tyrosine analogs used in mass spectrometry and other analytical techniques.
• Medicinal Chemistry: Provides a versatile scaffold for the design and synthesis of tyrosine kinase inhibitors and other targeted small molecules.

Basic Information

Product Name	D-Tyrosine-Obzl p-Tosylate
CAS No.	97984-63-9
Molecular Formula	C23H23NO6S
Molecular Weight	441.50 g/mol
Synonyms	D-Tyrosine-O-benzyl ester p-toluenesulfonate salt; (R)-2-Amino-3-(4-hydroxyphenyl)propanoic acid benzyl ester 4-methylbenzenesulfonate; H-D-Tyr-OBzl·TosOH; D-Tyrosine benzyl ester tosylate; Benzyl D-tyrosinate p-toluenesulfonate; D-Tyrosine-OBzl Tosylate; D-Tyrosine benzyl ester p-toluenesulfonic acid salt; D-Tyrosine-O-benzyl tosylate
EINECS	Contact for details

Quality Control

Our D-Tyrosine-Obzl p-Tosylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis to confirm enantiomeric excess, and identity confirmation via IR and NMR spectroscopy. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with research and pharmaceutical-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee (D-isomer)
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.