Description

2-Bromo-3-Oxopropanenitrile CAS NO 97925-42-3 is a versatile brominated nitrile building block essential for advanced organic synthesis. This compound is valued for its reactive bromine and carbonyl groups, enabling its use as a key intermediate in the construction of complex heterocyclic and pharmaceutical molecules. It is primarily sought by research chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for heterocyclic compounds and kinase inhibitors.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators.
• Material Science Research: Serves as a building block for creating functional polymers, liquid crystals, and advanced organic electronic materials.
• Chemical Biology & Proteomics: Employed in the design and synthesis of activity-based probes (ABPs) and other molecular tools for studying enzyme function.
• Cross-Coupling Reactions: Acts as an electrophilic partner in palladium-catalyzed cross-coupling reactions to form carbon-carbon bonds.
• Nucleophilic Substitution: The bromine atom is readily displaced by various nucleophiles, facilitating the introduction of diverse functional groups.

Basic Information

Product Name	2-Bromo-3-Oxopropanenitrile
CAS No.	97925-42-3
Molecular Formula	C3H2BrNO
Molecular Weight	147.96 g/mol
Synonyms	2-Bromo-3-oxopropanenitrile; 2-Bromo-3-oxopropiononitrile; Bromomalononitrile oxide; 3-Oxo-2-bromopropanenitrile; Bromoacetyl cyanide; α-Bromo-β-oxopropionitrile; 2-Bromomalonaldehyde nitrile; Bromomalonaldehyde nitrile
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-3-Oxopropanenitrile is manufactured and tested under a strict quality management system. Our products undergo rigorous quality testing, including HPLC, NMR, and GC analysis, to ensure compliance with industry standards and customer specifications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.