Description

n-Retinoylphenylalanine is a synthetic retinoid derivative that combines the biological activity of retinoic acid with the structural features of phenylalanine. This compound is of significant interest for its potential in modulating cellular differentiation and proliferation pathways. It is primarily utilized by research institutions and pharmaceutical developers focused on dermatology, oncology, and advanced cosmetic science for investigating novel therapeutic and cosmeceutical agents.

Application

• Pharmaceutical R&D: Serves as a key intermediate or active ingredient in the development of novel retinoid-based therapies for skin conditions and cancer.
• Cosmeceutical Actives: Incorporated into advanced anti-aging and skin-rejuvenation formulations for its potential effects on collagen synthesis and cellular turnover.
• Biochemical Research: Used as a molecular probe to study retinoic acid receptor (RAR) signaling pathways and their role in cell differentiation.
• Precision Synthesis: Acts as a building block for the synthesis of more complex, targeted retinoid compounds with enhanced stability or specificity.
• Dermatological Studies: Applied in in vitro and ex vivo models to evaluate efficacy and mechanisms of action for treating photoaging and acne.

Basic Information

Product Name	n-Retinoylphenylalanine
CAS No.	97885-88-6
Molecular Formula	C30H37NO3
Molecular Weight	459.62 g/mol
Synonyms	Retinoyl Phenylalanine; N-(All-trans-Retinoyl)-L-phenylalanine; N-Retinoyl-L-phenylalanine; Retinyl Phenylalanine; Phenylalanine Retinoate; Retinoic Acid Phenylalanine Amide; L-Phenylalanine, N-[(2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoyl]-; (2S)-2-[[(2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoyl]amino]-3-phenylpropanoic acid
EINECS	Contact for details

Quality Control

Our n-Retinoylphenylalanine is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation (IR, NMR) to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed chromatograms and spectral data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) or as specified on the label. This material is strictly light-sensitive and easily oxidized; prolonged exposure to air, light, or elevated temperatures should be avoided to maintain stability and potency.

Specification

Item	Specification
Appearance	Yellow to light orange powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Related Substances (HPLC)	Total impurities ≤ 2.0%
Heavy Metals	≤ 20 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.