Description

α-Arbutin is a highly purified, naturally derived glycosylated hydroquinone known for its potent skin-brightening properties. This compound matters for its superior stability and efficacy compared to its β-isomer, making it a premium active ingredient in advanced cosmetic formulations. It is primarily needed by manufacturers in the personal care, cosmetic, and pharmaceutical industries seeking to develop high-performance products for hyperpigmentation, age spots, and uneven skin tone.

Application

• Cosmetic & Skincare Formulations: As a key active in serums, creams, lotions, and essences for skin brightening and whitening.
• Treatment of Hyperpigmentation: Targeting melasma, age spots (lentigines), and post-inflammatory hyperpigmentation (PIH).
• Anti-Aging Products: Incorporated into formulations designed to reduce the appearance of dark circles and improve overall skin radiance.
• Pharmaceutical Topicals: Used in prescription or over-the-counter topical preparations for dermatological conditions involving pigmentation.
• Professional Treatments: A component in clinical-grade peels and professional skincare treatments administered by dermatologists.
• Sun Care Products: Added to after-sun and protective formulations to prevent and correct sun-induced skin darkening.

Basic Information

Product Name	α-Arbutin
CAS No.	84380-01-8
Molecular Formula	C12H16O7
Molecular Weight	272.25 g/mol
Synonyms	4-Hydroxyphenyl α-D-glucopyranoside; Arbutin α-anomer; α-Hydroquinone-D-glucopyranoside; p-Hydroxyphenyl-α-D-glucopyranoside; α-Arbutoside; HQ-α-Glc; (2R,3S,4S,5R,6S)-2-(Hydroxymethyl)-6-(4-hydroxyphenoxy)oxane-3,4,5-triol
EINECS	Contact for details

Quality Control

Our α-Arbutin is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets high-grade cosmetic and pharmaceutical standards. A comprehensive Certificate of Analysis (COA) detailing purity, heavy metals, residual solvents, and microbiological limits is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and easily oxidized; it is recommended to store under an inert atmosphere such as nitrogen for long-term preservation and to minimize exposure to air after opening.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 99.0%
Specific Rotation	+174° to +180° (c=1, in H2O)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 1.0% Hydroquinone ≤ 0.5 ppm
Microbiological Analysis	Total Plate Count ≤ 1000 CFU/g Yeast & Mold ≤ 100 CFU/g Absence of E. coli, Salmonella, S. aureus, P. aeruginosa

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.